EXTRACTABLE NUCLEAR ANTIGEN (ENA) PANEL, LIA

Test Name

Aliases

Abbreviations

Test Classification

GROUPED TEST

Department

SEROLOGY

Sub Department

AUTOIMMUNITY

TAT Category

ELAPSED (CONTINUOUS) TIME

Estimated TAT

TAT Units

DAYS

Test Requirements

Serum in plain tube (red top) or SST tube (yellow top) or in a separation vial. Centrifuge tubes within 1 hour. Separate centrifuged serum in plain tubes within 1 hour. EDTA plasma and citrate plasma samples are acceptable alternatives. Components include: SS-A / Ro 52kD, SS-A / Ro 60kD, SSB/ La, U 1-snRNP, Scl-70, PM-Scl AMA - M2, CENP B, DFS 70 antibody, dsDNA, Histones, Jo-1, Ku, Mi-2, Nucleosomes, PCNA, PO/RPP, SmD1

Clinical Utility

Diagnose systemic autoimmune rheumatic diseases (SARDs) e.g. SLE, mixed connective tissue disease (MCTD), scleroderma, Sjögren's syndrome, polymyositis etc. Can be done as a follow-up test for a positive ANA result.

Last Review

26th Feb 2026