Test Name
MATERNAL SCREEN, SECOND TRIMESTER [QUADRUPLE TEST (AFP, HCG, ESTRIOL, INHIBIN A)]
Aliases
2ND TRIMESTER MATERNAL SCREENING
Abbreviations
QUADRUPLE TEST
Test Classification
GROUPED TEST
Department
SPECIAL CHEMISTRY
Sub Department
-
TAT Category
ELAPSED (CONTINUOUS) TIME
Estimated TAT
144
TAT Units
HOURS
Test Requirements
1) Must be between 14 weeks - 22 weeks gestation on the date of SAMPLE COLLECTION
2) Ultrasound report required
3) Maternal weight (kg) needed
4) Race must be captured
5) A specific form with specific history needs to be filled IN FULL. Liaise with the technical team for this form.
Test components: AFP, HCG, ESTRIOL, INHIBIN A
Clinical Utility
Assess risk for fetal abnormalities i.e. Down syndrome (trisomy 21), Edward’s syndrome (trisomy 18) & neural tube defects (NTDs).
Last Review
26th Feb 2026