ANATOMIC PATHOLOGY

Formalin Fixed, Paraffin -Embedded Blocks. Residual tissue must be available on the block. Routinely, staining & reporting service is offered; however, stain & return service (IHC staining only without interpretation) is available for pathologists for interpretation & reporting at their end. Test may not be performed if no indication is found as determined by the reviewing pathologist. Ancillary tests may be indicated at additional cost as determined by the reviewing pathologist. NB: Cost depends on the number of IHC markers (resident pathologist available to give advice).

Formalin Fixed, Paraffin -Embedded Blocks. Residual tissue must be available on the block. Routinely, staining & reporting service is offered; however, stain & return service (IHC staining only without interpretation) is available for pathologists for interpretation & reporting at their end. Test may not be performed if no indication is found as determined by the reviewing pathologist. Ancillary tests may be indicated at additional cost as determined by the reviewing pathologist. NB: Cost depends on the number of IHC markers (resident pathologist available to give advice).

Provide clinical history, imaging findings, and prior therapy. Acceptable specimens: 1. Fresh breast tissue in 10% neutral buffered formalin (NBF); place in fixative immediately after excision OR 2. FFPE blocks OR 3. Unstained slides (3–5 µm). For IHC positively charged slides. Fixation requirements: 6–72 hours in 10% NBF; avoid over-fixation or under-fixation. Tissue quality: Representative tumor tissue with minimal crush or thermal artifact. Test components: Histology with ER, PR, and HER 2 IHC.

Formalin fixed paraffin embedded block(s) +/- H&E stained slides. Original histology (H&E) report plus detailed clinical information inclusive of imaging findings where applicable is MANDATORY. Does NOT include IHC. If required, additional charges for IHC apply.

Formalin fixed, paraffin embedded blocks. Residual tissue with tumor must be available on the block. Transport at room temperature (20-25 degrees C); protect from excessive heat. Clinical history and original H&E report are required.

Formalin Fixed, Paraffin -Embedded Blocks. Residual tissue must be available on the block. Routinely, staining & reporting service is offered; however, stain & return service (IHC staining only without interpretation) is available for pathologists for interpretation & reporting at their end. Test may not be performed if no indication is found as determined by the reviewing pathologist. Ancillary tests may be indicated at additional cost as determined by the reviewing pathologist. NB: Cost depends on the number of IHC markers (resident pathologist available to give advice).

TEST ORDERING INSTRUCTIONS: Fill out test request form fully & legibly. Provide complete history including last menstrual period (LMP)/ if postmenopausal; contraceptive issue; specific indication (e.g. routine screening vs. follow up of previous abnormal results); appearance of the cervix at the time of sampling. SAMPLE TYPE: Smear of the cervix (on intact, labeled slides). Avoid collection during menses. CONTAINER/ PRESERVATIVE Immediately fixed smears which are labeled with patient details; glass slides should be intact (not broken). Avoid air drying.

TEST ORDERING INSTRUCTIONS: Fill out test request form fully & legibly. Provide complete history including last menstrual period (LMP)/ if postmenopausal; contraceptive issue; specific indication (e.g. routine screening vs. follow up of previous abnormal results); appearance of the cervix at the time of sampling. SAMPLE TYPE: Smear of the cervix (on intact, labeled slides). Avoid collection during menses. CONTAINER/ PRESERVATIVE Immediately fixed smears which are labeled with patient details; glass slides should be intact (not broken). Avoid air drying.

TEST ORDERING INSTRUCTIONS: Fill out test request form fully & legibly. Provide your contact information & complete history with relevant investigation details (lab, imaging). Specify the exact fluid source (e.g. pleural fluid, ascitic fluid, CSF, urine, right knee joint fluid etc.). SAMPLE TYPES: Fluid from variable sources. Exact anatomic site and where applicable laterality (left or right) must be specified. CONTAINER/ PRESERVATIVE Provide ≥10mL fluid in sterile, labeled, leak-proof container.

TEST ORDERING INSTRUCTIONS: Fill out test request form fully & legibly. Provide clinical history. Specify the exact sample type, anatomic site, laterality (where applicable e.g. left vs right) from where the FNA should be obtained. SAMPLE TYPES: Variable e.g. thyroid, breast, lymph node etc. Exact anatomic site must be specified by the person doing collection. COMPONENTS: FNA collection / procedure (requires patient to be physically present) AND reporting (laboratory assessment). CONTAINER/ PRESERVATIVE Fixed smears which are labeled with patient details; glass slides should be intact (not broken). 2 slides should be air dried then methanol fixed; another 2 should be placed directly in ethanol fixative without air drying.