Category
SPECIAL CHEMISTRY.
Sub Category
TUMOR MARKER
Synonyms/Aliases
5-OH-INDOLEACETIC ACID.
Abbreviations
5-HIAA
Type
INDIVIDUAL TEST
Results
RESULTS READY/ REPORTED IN 7 WORKING DAYS
Method
CHROMATOGRAPHY.
Temp
REFRIGERATED. ROOM (AMBIENT) TEMPERATURE IS NOT ACCEPTABLE
Setup
BATCHED.
Components Parameters
NOT APPLICABLE.
PRE-ANALYTIC CONSIDERATIONS
Test Ordering Instructions
FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. TOTAL VOLUME OF COLLECTED 24 HOUR URINE IS REQUIRED. PROVIDE CLINICAL HISTORY & PATIENT'S CURRENT DRUG HISTORY (MULTIPLE DRUGS CAN INCREASE OR DECREASE 5-HIAA LEVELS; CONSULT PATHOLOGIST IF IN DOUBT).
Patient preparation
ACCURATELY TIMED 24 HOUR COLLECTION (E.G. 6A.M., DAY 1 TO 6A.M., DAY 2) IS CRUCIAL FOR RESULT ACCURACY. COLLECT URINE IN A CLEAN WIDE MOUTH CONTAINER & TRANSFER ENTIRE COLLECTION INTO THE CONTAINER THAT WAS PROVIDED BY THE LAB. REFRIGERATE DURING COLLECTION. KEEP OUT OF REACH OF CHILDREN (CONTAINS CORROSIVE SUBSTANCES). DO NOT CONSUME FOODS RICH IN SEROTONIN (E.G. AVOCADOS, BANANAS, PINEAPPLE, MELONS, TOMATOES, EGGPLANTS, NUTS ETC.) FOR 48-72 HOURS PRIOR TO SAMPLE COLLECTION. AVOID STRENUOUS EXERCISE.
Sample type
24 HOUR URINE. TO BE KEPT IN DARK E.G. IN DARK CONTAINER OR WRAPPED IN ALUMINIUM FOIL.
Container/ preservative
CLEAN CONTAINER WITH 10ML OF 6N HCL PRESERVATIVE ISSUED BY THE LAB.
Sample volume
10ML ALIQUOT OF 24 HOUR URINE. ORIGINAL (TOTAL) VOLUME IN ML MUST BE SPECIFIED ON THE REQUEST FORM.
Rejection criteria
LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE (E.G. SPOT URINE SAMPLES; EXPOSED TO LIGHT; WITHOUT PRESERVATIVE); INSUFFICIENT SAMPLE.
Other Instructions
- N/A
Reference intervals
AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.
Clinical Utility
A SEROTONIN METABOLITE & TUMOR MARKER USED IN THE DIAGNOSIS & MONITORING OF CARCINOID TUMORS.
Test Limitations/ Confounders
DIETARY & DRUG RESTRICTIONS APPLY. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS & RESULTS OF OTHER DIAGNOSTIC WORK-UP E.G. IMAGING, TISSUE BIOPSY FINDINGS.