Category
SPECIAL CHEMISTRY.
Sub Category
AUTOIMMUNE
Synonyms/Aliases
CARDIOLIPIN ANTIBODIES; ANTIPHOSPHOLIPID ANTIBODIES
Abbreviations
ACA; ACL Ab; ACA IgA, IgG, IgM
Type
PROFILE/ PANEL (BUNDLED TESTS)
Results
RESULTS READY/ REPORTED IN 5WORKING DAYS
Method
IMMUNOASSAY
Temp
REFRIGERATED
Setup
BATCHED.
Components Parameters
ACA IgA, ACA IgG AND ACA IgM
PRE-ANALYTIC CONSIDERATIONS
Test Ordering Instructions
FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. INDIVIDUAL ANTIBODIES (IgA, IgG OR IgM) CAN BE ORDERED. IF ANTIBODY TYPE IS NOT SPECIFIED, ALL THREE ANTIBODIES ARE SELECTED BY DEFAULT
Patient preparation
NO PREPARATION REQUIRED.
Sample type
SERUM
Container/ preservative
SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.
Sample volume
AT LEAST 3ML
Rejection criteria
LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.
Other Instructions
CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.
Reference intervals
INTERPRETIVE DATA IS PROVIDED ON THE REPORT.
Clinical Utility
EVALUATION OF ANTIPHOSPHOLIPID SYNDROME (PHOSPHOLIPID ANTIBODY SYNDROME). EVALUATION OF PATIENTS WITH UNEXPLAINED THROMBOSIS, RECURRENT MISCARRIAGES ETC.
Test Limitations/ Confounders
POSITIVE RESULTS MAY OCCUR IN OTHER AUTOIMMUNE DISORDERS E.G. SLE, RHEUMATOID ARTHRITIS, SJOGREN'S SYNDROME & IN THESE CONDITIONS MAY BE ASSOCIATED WITH INCREASED THROMBOTIC RISK. TRANSIENT POSITIVITY CAN OCCUR AND REPEAT TESTING IS ADVISED AFTER 12 WEEKS TO DEMONSTRATE PERSISTENCE OF ANTIBODIES.