Category
SEROLOGY/ IMMUNOLOGY
Sub Category
INFECTIOUS
Synonyms/Aliases
EPSTEIN-BARR VIRUS (EBV) ANTIBODY TO NUCLEAR ANTIGEN; EBV NUCLEAR ANTIBODY; EBV NUCLEAR ANTIGEN ANTIBODIES.
Abbreviations
EBV-NA, EBNA Ab
Type
INDIVIDUAL TEST.
10 DAYS
10 WORKING DAYS
Method
IMMUNOASSAY.
Temp
AMBIENT (4 DAYS), REFRIGERATED (7 DAYS), FROZEN (30 DAYS).
Setup
BATCHED.
Components Parameters
N/A
PRE-ANALYTIC CONSIDERATIONS
Test Ordering Instructions
FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. RESULTS ARE BEST INTERPRETED IN CONJUNCTION WITH OTHER EBV SEROLOGY TESTS (EBV VCA IgM AND IgG) THEREFORE ORDERING AS A PROFILE IS RECOMMENDED.
Patient preparation
N/A
Sample type
SERUM
Container/ preservative
SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.
Sample volume
2-3 ML.
Rejection criteria
LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE; HEMOLYZED, LIPEMIC, ICTERIC SAMPLES.
Other Instructions
CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.
Reference intervals
NEGATIVE.
Clinical Utility
DIAGNOSIS OF EBV INFECTION (INFECTIOUS MONONUCLEOSIS). TYPICALLY APPEARS DURING CONVALESCENCE PHASE I.E. 3-4 MONTHS AFTER SYMPTOMATIC DISEASE.
Test Limitations/ Confounders
SOME PEOPLE NEVER DEVELOP EBNA. FALSE POSITIVE RESULTS CAN OCCUR. RESULTS SHOULD BE INTERPRETED TAKING INTO ACCOUNT THE CLINICAL CONTEXT.