Category
Anatomic Pathology
Sub Category
Surgical/ Histopathology
Synonyms/Aliases
Histopathology Consultation, Wet/ Unprocessed Tissue; Surgical Pathology Consultation, Wet/ Unprocessed Tissue.
Abbreviations
N/A
Type
Individual Test
14 Days
Results Ready in 14 Days
Method
Grossing, Tissue Processing, Staining And Microscopy
Temp
Room temperature; refrigerated is also acceptable.
Setup
Mon-Fri
Components Parameters
N/A
Pre-analytic Considerations
N/A
Test Ordering Instructions
Fill out test request form fully & legibly. Provide your contact information & complete history including suspected diagnosis & relevant investigation details (lab, imaging). Specify the exact sample type, procedure done, anatomic site, laterality where applicable (e.g. Left vs right) and the fixative used. Time of insertion into fixative is required for Mastectomy specimens.
Patient preparation
N/A
Sample type
A Variety Of Specimens Are Categorized As "Large" Based On Hybrid Criteria (Size/ Complexity/ Cost Of Processing/ Pathologist Time) E.g. Whole Organ(S), Large Amputation, Or A Large Biopsy Of Part Of An Organ. Examples: Prostatectomy, Mastectomy, Colectomy, Esophagectomy, Gastrectomy, Extremity (Limb) Amputation Or Disarticulation, Nephrectomy, Laryngectomy, Hepatectomy, Lung Resection, Splenectomy, Hysterectomy (With Or Without Adnexae), Lung (Segment, Lobar Or Total) Resection, Pancreas, Vulvectomy Specimens. Also, Soft Tissue Lesions ≥5 cm In Maximum Dimension, Bone Resections For Neoplasms, Eye Enucleation Or Exenteration, Gall Bladder & Porta Hepatis Radical Resection Etc.
Container/ preservative
10% formalin (10% neutral buffered formalin preferred) in appropriate size, leak proof container. Immerse specimen into formalin within 30 minutes of removal.
Sample volume
Volume of formalin to tissue of ≥10:1
Rejection criteria
Labeling Issue (Unlabeled/ Mislabeled Blocks); Missing Request Form; Request Form Not Accompanied By Sample; Mismatch Between Request Form & Sample Details; Missing Age/ Gender; Wrong Sample Type; Incorrect Preservative; Insufficient Sample; Empty Sample Containers.
Other Instructions
Incorrect preservative (e.g. Placing sample for Histology in normal saline) is likely to resut in sample Deterioration/ Putrefaction, Suboptimal evaluation & inability to give a diagnosis.
Reference intervals
Negative for disease / Malignancy
Clinical Utility
Provides diagnosis for diseases, from benign to malignant.
Test Limitations/ Confounders
Poorly fixed tissue