Category
SPECIAL CHEMISTRY.
Sub Category
ENDOCRINE.
Synonyms/Aliases
SOMATOMEDIN-C, SULFATION FACTOR.
Abbreviations
IGF-1; IGF1; SM-C.
Type
INDIVIDUAL TEST
5 Days
RESULTS READY/ REPORTED IN 5 WORKING DAYS.
Method
IMMUNOASSAY.
Temp
FROZEN (-20°C) PREFERRED OR REFRIGERATED. THERE IS LIMITED STABILITY AT ROOM (AMBIENT) TEMPERATURE AND THIS SHOULD BE AVOIDED.
Setup
BATCHED.
Components Parameters
NOT APPLICABLE.
PRE-ANALYTIC CONSIDERATIONS
Test Ordering Instructions
FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.
Patient preparation
10-12HOURS FASTING REQUIRED. FASTING MEANS THAT ONLY WATER AND PRESCRIBED MEDICATION ARE PERMITTED DURING THE FASTING PERIOD.
Sample type
SERUM.
Container/ preservative
SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.
Sample volume
2 ML SERUM.
Rejection criteria
LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE; NON-FASTING SAMPLE.
Other Instructions
CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.
Reference intervals
AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.
Clinical Utility
DIAGNOSIS OF GROWTH DISORDERS E.G. SHORT STATURE/ DWARFISM, GIGANTISM, ACROMEGALY FROM PITUITARY & HYPOTHALAMIC DISORDERS. EVALUATION OF GROWTH HORMONE EXCESS AND GROWTH HORMONE DEFICIENCY.
Test Limitations/ Confounders
LEVELS INFLUENCED BY CHRONIC INFLAMMATORY STATES, NUTRITIONAL DISORDERS, PREGNANCY ETC. IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS.