Category
SEROLOGY/ IMMUNOLOGY
Sub Category
AUTOIMMUNE.
Synonyms/Aliases
ANTI-INTRINSIV FACTOR; INTRINSIC FACTOR BLOCKING ANTIBODY.
Abbreviations
IFAB.
Type
INDIVIDUAL TEST.
7 DAYS
7 WORKING DAYS.
Method
IMMUNOASSAY.
Temp
REFRIGERATED (2℃-8℃):7D, F (-20℃): 30D.
Setup
BATCHED.
Components Parameters
N/A
PRE-ANALYTIC CONSIDERATIONS
Test Ordering Instructions
FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.
Patient preparation
N/A
Sample type
SERUM.
Container/ preservative
SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.
Sample volume
AT LEAST 2 ML.
Rejection criteria
LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.
Other Instructions
CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.
Reference intervals
INTERPRETIVE DATA IS PROVIDED ON THE REPORT.
Clinical Utility
HIGHLY SPECIFIC FOR DIAGNOSIS OF PERNICIOUS ANAEMIA WHICH IS A CAUSE OF MEGALOBLASTIC ANEMIA.
Test Limitations/ Confounders
VITAMINS B12 ADMINISTRATION WITHIN THE PREVIOUS 1 WEEK CAN RESULT IN FALSE POSITIVE INTRINSIC FACTOR ANTIBODY RESULTS AND SHOULD BE AVOIDED. TEST IS POSITIVE ONLY IN 60% OF PATIENTS WITH PERNICIOUS ANEMIA.