Category
Molecular Genetic Pathology & Cytogenetics
Sub Category
Cytogenetics
Synonym/Aliases
N/A
Abbreviations
N/A
Type
Individual Test
Results
RESULTS READY WITHIN 15 - 18 DAYS
Method
CHROMOSOMAL ANALYSIS VIA CELL CULTURE, EXPOSURE TO MITOGENS, BANDED KARYOGRAMS & MICROSCOPIC ANALYSIS OF METAPHASE CELLS.
Temp
KEPT AT ROOM TEMPERATURE 1 DAY, 2-8ºC 1 DAY
Setup
BATCHED
Components Parameters
- N/A
PRE-ANALYTIC CONSIDERATIONS
Test Ordering Instructions
FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. PROVIDE CLINICAL HISTORY. NOTIFY THE LAB PRIOR TO COLLECTION. CONSIDER CHROMOSOMAL MICROARRAY (CMA) AS A POSSIBLE ALTERNATIVE TEST.
Patient preparation
IN CASE OF SELF SAMPLING, MANUFACTURER'S INSTRUCTIONS FOR SELF COLLECTED SPECIMENS APPLY.
Sample type
WHOLE BLOOD OR BONE MARROW IN SODIUM HEPARIN.
Container/ preservative
SODIUM HEPARIN (DARK GREEN TOP) VACUTAINER.
Sample volume
3 ML
Rejection criteria
LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.
Other Instructions
AVOID OTHER TYPES OF HEPARIN VACUTAINERS E.G. LITHIUM HEPARIN.
Reference intervals
INTERPRETIVE DATA IS PROVIDED ON THE REPORT.
Clinical Utility
DETECTS NUMERICAL & STRUCTURAL CHROMOSOMAL ABNORMALITIES WITHIN THE ASSAY'S LIMIT OF DETECTION.
Test Limitations/ Confounders
A NORMAL RESULT DOES NOT COMPLETELY EXCLUDE GENETIC DISORDERS E.G. SINGLE GENE DISORDERS, SUBMICROSCOPIC CYTOGENETIC ABNORMALITIES BELOW THE ASSAY'S DETECTION LIMIT.