Test Name
KARYOTYPING, COUPLE (BLOOD)
Aliases
HUSBAND AND WIFE KARYOTYPING
Abbreviations
-
Test Classification
GROUPED TEST
Department
MOLECULAR PATHOLOGY
Sub Department
GENETIC AND HEREDITARY DISORDERS
TAT Category
ELAPSED (CONTINUOUS) TIME
Estimated TAT
20
TAT Units
DAYS
Test Requirements
Peripheral blood in sodium heparin vacutainer. Collected from EACH member of the couple(husband and wife). Appropriately labeled clearly distinguishing from whom each sample has come. Clinical history/ indication required. Specific form to be filled before sending out.
Clinical Utility
Typically ordered for evaluation of recurrent pregnancy losses/ bad obstetric history. Detects numerical & structural chromosomal abnormalities within the assay's limit of detection. This cytogenetic analysis is essential for understanding genetic contributions to diseases and providing targeted medical care, A normal result does not completely exclude genetic disorders e.g. single gene disorders, submicroscopic cytogenetic abnormalities below the assay's detection limit. Where there is a high residual index of suspicion following a normal result, other tests can be considered e.g. chromosomal microarray (depends on the clinical context).
Last Review
26th Feb 2026