Category
SPECIAL CHEMISTRY.
Sub Category
ANEMIA & NUTRITION.
Synonyms/Aliases
METHYLMALONATE, SERUM.
Abbreviations
MMA.
Type
INDIVIDUAL TEST.
7 Days
RESULTS READY/ REPORTED IN 7 WORKING DAYS.
Method
LC-MS/MS.
Temp
R (2℃-8℃):3D; F (-20℃):14D. SAMPLES AT ROOM TEMPERATURE ARE NOT ACCEPTABLE.
Setup
BATCHED.
Components Parameters
NOT APPLICABLE.
PRE-ANALYTIC CONSIDERATIONS
Test Ordering Instructions
FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.
Patient preparation
NOT APPLICABLE.
Sample type
SERUM (SEPARATE THE SAMPLE WITHIN 1 HOUR AFTER COLLECTION).
Container/ preservative
SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.
Sample volume
AT LEAST 3MLSEPARATED WITHIN 1 HOUR AFTER COLLECTION.
Rejection criteria
LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.
Other Instructions
CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.
Reference intervals
AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.
Clinical Utility
DIAGNOSE AND MONITOR METHYLMALONIC ACIDEMIA AND LATENT VITAMIN B12 DEFICIENCY (BORDERLINE LOW VITAMIN B12 LEVELS).
Test Limitations/ Confounders
DIET AND NUTRITIONAL STATUS INFLUENCE LEVELS.