CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.
Reference intervals
DEPENDENT ON AGE, GENDER & TANNER STAGE.
Clinical Utility
CONFIRMATION OF TRUE TESTERONE STATUS IN PATIENTS WITH ACTUAL OR SUSPECTED ABNORMAL SHBG LEVELS (ABNORMAL SHBG LEVELS MAY OCCUR IN A VARIETY OF SITUATIONS E.G. OBESITY, THYROID DISEASE, LIVER DISEASE, WITH SOME DRUGS ETC.). EVALUATION OF SUSPECTED MALE HYPOGONADISM (LOW LIBIDO, ERECTILE DYSFUNCTION, ETC.). AS A FOLLOW UP TEST FOR ABNORMAL SEMENALYSIS RESULTS (E.G. AZOOSPERMIA, OLIGOSPERMIA). ASSESSMENT OF INFERTILITY, PRECOCIOUS MALE PUBERTY, AMENORRHEA, OLIGOMENORRHEA. EVALUATION OF VIRILIZATION IN FEMALES [E.G. FROM PCOS, ANDROGEN SECRETING OVARIAN OR PITUITARY TUMORS, CONGENITAL ADRENAL HYPERPLASIA ETC.). EVALUATION OF AMBIGUOUS GENITALIA AND DISORDERS OF SEX DEVELOPMENT (DSDs)].
Test Limitations/ Confounders
IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS.