Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE.

Synonyms/Aliases

N/A.

Abbreviations

N/A.

Type

INDIVIDUAL TEST.

5 DAYS

RESULTS READY/ REPORTED IN 5 WORKING DAYS.

Method

IMMUNOASSAY.

Temp

REFRIGERATED.

Setup

BATCHED.

Components Parameters

N/A.

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

COLLECT SAMPLES BETWEEN 8-10A.M.

Sample type

SERUM. HEPARIN PLASMA IS AN ACCEPTABLE ALTERNATE SPECIMEN.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

2ML

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.

Reference intervals

DEPENDENT ON AGE, GENDER & TANNER STAGE.

Clinical Utility

CONFIRMATION OF TRUE TESTERONE STATUS IN PATIENTS WITH ACTUAL OR SUSPECTED ABNORMAL SHBG LEVELS (ABNORMAL SHBG LEVELS MAY OCCUR IN A VARIETY OF SITUATIONS E.G. OBESITY, THYROID DISEASE, LIVER DISEASE, WITH SOME DRUGS ETC.). EVALUATION OF SUSPECTED MALE HYPOGONADISM (LOW LIBIDO, ERECTILE DYSFUNCTION, ETC.). AS A FOLLOW UP TEST FOR ABNORMAL SEMENALYSIS RESULTS (E.G. AZOOSPERMIA, OLIGOSPERMIA). ASSESSMENT OF INFERTILITY, PRECOCIOUS MALE PUBERTY, AMENORRHEA, OLIGOMENORRHEA. EVALUATION OF VIRILIZATION IN FEMALES [E.G. FROM PCOS, ANDROGEN SECRETING OVARIAN OR PITUITARY TUMORS, CONGENITAL ADRENAL HYPERPLASIA ETC.). EVALUATION OF AMBIGUOUS GENITALIA AND DISORDERS OF SEX DEVELOPMENT (DSDs)].

Test Limitations/ Confounders

IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS.