Category
SPECIAL CHEMISTRY.
Sub Category
TUMOR MARKER.
Synonyms/Aliases
N/A.
Abbreviations
TG.
Type
INDIVIDUAL TEST.
5 DAYS
RESULTS READY/ REPORTED IN 5 WORKING DAYS.
Method
IMMUNOASSAY.
Temp
FROZEN PREFERRED. SAMPLES AT AMBIENT (ROOM) TEMPERATURE ARE NOT ACCEPTABLE.
Setup
BATCHED.
Components Parameters
N/A.
PRE-ANALYTIC CONSIDERATIONS
Test Ordering Instructions
FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. CO-ORDER THYROGLOBULIN ANTIBODIES (ATA; ATG) WHICH CAN LEAD TO FALSE NEGATIVE RESULTS. ACCURACY OF THYROGLOBULIN RESULTS IS DEPENDENT ON ATA/ ATG STATUS.
Patient preparation
NOT APPLICABLE.
Sample type
SERUM.
Container/ preservative
SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.
Sample volume
AT LEAST 2 ML.
Rejection criteria
LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.
Other Instructions
CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.
Reference intervals
AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.
Clinical Utility
MONITORING TREATMENT RESPONSE & ASSESSING TUMOR RECURRENCE IN PATIENTS WITH THYROID CANCER E.G. WHO HAVE UNDERGONE TOTAL THYROIDECTOMY.
Test Limitations/ Confounders
IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. THYROGLOBULIN ANTIBODIES (ATA; ATG) CAN LEAD TO FALSE NEGATIVE THYROGLOBULIN RESULTS WHEN THE TESTING METHODOLOGY IS AN IMMUNOASSAY. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS.