TREPHINE BONE MARROW BIOPSY/ CLOT SECTION (REPORTING ONLY)
Test Name
TREPHINE BONE MARROW BIOPSY/ CLOT SECTION (REPORTING ONLY)
Aliases
BM BIOPSY REPORTING
Abbreviations
BMB
Test Classification
INDIVIDUAL
Department
HEMATOLOGY
Sub Department
GENERAL
TAT Category
ELAPSED (CONTINUOUS) TIME
Estimated TAT
2
TAT Units
DAYS
Test Requirements
TEST ORDERING:
Fill out test request form fully & legibly. CBC, concurrent PBF, referrer's contact information and detailed medical history are also required (bone marrow history form can be shared). Relevant history includes suspected diagnosis & any relevant investigation details (lab, imaging) as applicable. Specify the exact sample type(s) collected, anatomic site & laterality (e.g. left posterior superior iliac spine) and the fixative used.
CONTAINER/ PRESERVATIVE
Trephine biopsy in 10% neutral buffered formalin in a leak proof container OR if the biopsy is already processed, in formalin fixed paraffin embedded block (FFPE).
GUIDANCE - YOUTUBE VIDEOS
For preparation of peripheral blood films, review this YouTube video: https://www.youtube.com/watch?v=kafqQZmrgQE
For preparation of 10% neutral buffered formalin, see this video: https://www.youtube.com/watch?v=Vr2y4-fAOs4
Clinical Utility
Variable e.g. assess unexplained cytopenias (anemia, leukopenia, thrombocytopenia), unexplained cytoses (polycythemia, leukocytosis, thrombocytosis), suspected malignancy or infiltration (leukemia, lymphoma, myeloproliferative neoplasms, metastatic disease), pyrexia of unknown origin, infectious diseases (e.g. leishmaniasis), B symptoms (unintentional weight loss, drenching night sweats, fever) etc.