MOLECULAR PATHOLOGY

For EACH alleged sibling: Passport photo, ID copy (birth certificate in case of minors) & signed consent form. Consent, passport photo and ID copy of a parent is mandatory where the alleged sibling is a minor. Not intended for medicolegal purposes which requires a court order. EDTA whole blood sample of each person tested with appropriate labeling.

For EACH alleged sibling: Passport photo, ID copy (birth certificate in case of minors) & signed consent form. Consent, passport photo and ID copy of a parent is mandatory where the alleged sibling is a minor. Not intended for medicolegal purposes which requires a court order. EDTA whole blood sample of each person tested with appropriate labeling.

Tumor containing FFPE block (>10% of tumor). Tumor-containing tissue was fixed in 10% neutral buffered formalin for a duration of 6 to 72 hours. If tissue is provided, then tissue processing and FFPE block-making charges will be applicable. Clinical history and histopathology report are required.

Whole blood or bone marrow in EDTA. Prompt delivery. Time sensitive - notify central lab in advance.

NB: This test is very time sensitive with a high risk for failed karyotyping; preferred test is CHROMOSOMAL MICROARRAY, PRODUCTS OF CONCEPTION (POC)/ STILLBIRTH!!! Viable foetal tissue/ products of conception (POCs) in tissue culture media (or RPMI/ Hank's/ Ringer's lactate/ normal saline to which 3-4 drops of gentamicin have been added). Promptly deliver. Notify central lab in advance. First trimester loss: At least 10g chorionic villi/ POCs in culture media or normal saline with antibiotics. (3-4 drops of procaine penicillin or gentamicin). Second trimester and beyond: dual specimens preferred i.e. 1) placental biopsy from foetal side within 1 inch of the placental insertion site plus 2) foetal tissue (e.g. muscle biopsy from medial aspect of the thigh or foetal toe). Specimens to be submitted in culture media or normal saline with antibiotics. (3-4 drops of procaine penicillin or gentamicin).

2-3 mL of serum or 2-3 mL of EDTA plasma. NB: Order MUST be clarified if the doctor simply states HBV PCR i.e. clarification on whether qualitative PCR should be done (used for DIAGNOSIS; code MP2313) or whether quantitative PCR/ viral load should be done (used for TREATMENT MONITORING where diagnosis is ALREADY established). If the order states viral load, this is synonymous with QUANTItative PCR and this code should NOT be selected. Instead code MP2310 should be selected. SHIPPING/ TRANSPORTATION REQUIREMENTS Shipping Temperature: Refrigerated ANALYTE STABILITY Room Temperature: 7 days at 20-25°C │ Refrigerated: 1 month at 2-8°C │ Frozen: 1 month at -20°C

3-5 ml of EDTA whole blood is required or 3-5 ml of EDTA bone marrow, depending on clinical history.

Nasopharyngeal (NP) swab/ oropharyngeal (OP) swab in viral transport media (VTM).

Bone marrow in sodium heparin vacutainer. Clinical history/ indication required. Specific form to be filled before sending out.

Serum in plain tube (red top) or SST tube (yellow top) or in a separation vial. Centrifuge tubes within 1 hour. Separate centrifuged serum in plain tubes within 1 hour. Test components: Yellow fever virus IgM, Yellow fever virus IgG, Yellow fever virus RNA (RT-PCR)