Test Name
CHROMOSOMAL MICROARRAY, PRODUCTS OF CONCEPTION (POC)/ STILLBIRTH
Aliases
SNP MICROARRAY, ARRAY CGH, ARRAY FETO. CHROMOSOMAL ARRAY PRODUCTS OF CONCEPTION (POC)/ STILLBIRTH
Abbreviations
POC ACGH, POC CMA, CNV+SNP ARRAY PRODUCTS OF CONCEPTION (POC)/ STILLBIRTH
Test Classification
INDIVIDUAL
Department
MOLECULAR PATHOLOGY
Sub Department
GENETIC AND HEREDITARY DISORDERS
TAT Category
ELAPSED (CONTINUOUS) TIME
Estimated TAT
12
TAT Units
DAYS
Test Requirements
Viable fetal tissue/ products of conception (POCs) in tissue culture media (or RPMI/ Hank's/ Ringer's lactate/ normal saline to which 2-3 drops of gentamicin have been added).
First trimester loss: POCs in culture media or normal saline with antibiotics.
Second trimester and beyond: dual specimens preferred i.e. 1) placental biopsy from fetal side within 1 inch of the placental insertion site plus 2) fetal tissue (e.g. Muscle biopsy from medial aspect of the thigh or fetal toe). Each biopsy should be at least ~5x5 mm (~size of pencil rubber/ eraser) or larger.
Clinical Utility
Diagnosis of pregnancy losses arising from genomic copy number variations e.g. aneuploidies (e.g. trisomies, Turner syndrome, Klinefelter syndrome), mosaicism >20%, microdeletions & microduplications within the assay's resolution. Cannot detect balanced chromosomal rearrangements, single gene disorders, mosaicism <20% etc. Higher risk of uncertain & incidental findings than karyotyping.
Last Review
26th Feb 2026

