Serology – ScanLab Center

12 Dec

CYTOMEGALOVIRUS IgG

December 12, 2022June 5, 2023vincentochiengde

Category

SEROLOGY/ IMMUNOLOGY

Sub Category

INFECTIOUS

Synonyms/Aliases

TORCH IGG.

Abbreviations

CMV IgG

^Type

INDIVIDUAL TEST.

^{24-48 Hrs}

24-48 Hrs

^Method

AUTOMATED IMMUNOASSAY.

^Temp

AMBIENT (8 HOURS), REFRIGERATED (7 DAYS), FROZEN (30 DAYS).

^Setup

ALL WORKING DAYS

Components Parameters

N/A

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. SPECIFY EXACT ANTIBODY TYPE REQUIRED E.G.CMV IgG RATHER THAN CMV SEROLOGY.

Patient preparation

N/A

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

2ML

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE; HEMOLYZED, LIPEMIC, ICTERIC SAMPLES.

Other Instructions

CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.

Reference intervals

APPROPRIATE VALUES PROVIDED WITH REPORT.

Clinical Utility

IgG POSITIVITY IS CONSISTENT WITH PAST EXPOSURE TO CMV INFECTION.

Test Limitations/ Confounders

SOME ADULTS ARE CARRIERS OF CMV VIRUS WHICH IS NORMAL.

12 Dec

CYTOMEGALOVIRUS IgM

December 12, 2022June 5, 2023vincentochiengde

Category

SEROLOGY/ IMMUNOLOGY

Sub Category

INFECTIOUS

Synonyms/Aliases

TORCH IGM

Abbreviations

CMV IgM

^Type

INDIVIDUAL TEST.

^{24-48 HRS}

24-48 HRS

^Method

AUTOMATED IMMUNOASSAY.

^Temp

AMBIENT (8 HOURS), REFRIGERATED (7 DAYS), FROZEN (30 DAYS).

^Setup

ALL WORKING DAYS.

Components Parameters

N/A

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. SPECIFY EXACT ANTIBODY TYPE REQUIRED E.G.CMV IgM RATHER THAN CMV SEROLOGY.

Patient preparation

N/A

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

2ML

Rejection criteria

Other Instructions

Reference intervals

APPROPRIATE VALUES PROVIDED WITH REPORT.

Clinical Utility

A POSITIVE RESULT IS CONSISTENT WITH CURRENT/ RECENT INFECTION WITH CYTOMEGALOVIRUS (CMV). IgM IS THE FIRST ANTIBODY PRODUCED BY THE IMMUNE SYSTEM IN RESPONSE TO INFECTION.

Test Limitations/ Confounders

N/A

12 Dec

VDRL / RPR

December 12, 2022June 6, 2023vincentochiengde

Category

SEROLOGY/ IMMUNOLOGY

Sub Category

INFECTIOUS

Synonyms/Aliases

VENEREAL DISEASE RESEARCH LAB; RAPID PLASMA REAGIN.

Abbreviations

VDRL; RPR.

^Type

INDIVIDUAL TEST.

^{2-3 HRS}

RESULTS READY IN 2-3 HOURS.

^Method

FLOCCULATION.

^Temp

AMBIENT (24 HOURS), REFRIGERATED (7 DAYS), FROZEN (21 DAYS).

^Setup

ALL WORKING DAYS.

Components Parameters

N/A

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

N/A

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

2 ML

Rejection criteria

Other Instructions

Reference intervals

NEGATIVE.

Clinical Utility

SCREENING FOR SYPHILIS INFECTION; MONITORING TREATMENT RESPONSE (DECLINING TITRES).

Test Limitations/ Confounders

REQUIRES FOLLOW-UP TESTING WITH A TREPONEMAL TEST E.G. TPHA IF NOT ALREADY PERFORMED (NO SINGLE SEROLOGICAL TEST CAN DIAGNOSE ACTIVE SYPHILIS).

12 Dec

WIDAL SCREENING

December 12, 2022June 6, 2023vincentochiengde

Category

SEROLOGY/ IMMUNOLOGY

Sub Category

INFECTIOUS

Synonyms/Aliases

SALMONELLA TYPHI - O & H ANTIGEN, SALMONELLA PARATYPHI A - H ANTIGEN, SALMONELLA PARATYPHI B - H ANTIGEN.

Abbreviations

N/A

^Type

PROFILE/ PANEL (BUNDLED TESTS).

^{4-5 Days}

4-5 WORKING DAYS

^Method

AGGLUTINATION.

^Temp

AMBIENT (24 HOURS), REFRIGERATED (7 DAYS), FROZEN (30 DAYS).

^Setup

ALL WORKING DAYS.

Components Parameters

"O" ANTIGEN, "H" ANTIGEN.

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

N/A

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

2 ML

Rejection criteria

Other Instructions

Reference intervals

NEGATIVE.

Clinical Utility

DETECTS THE PRESENCE OF SERUM AGGLUTININS (H AND O) IN PATIENTS SERUM WITH TYPHOID AND PARATYPHOID FEVER.

Test Limitations/ Confounders

CROSS-REACTIVITY WITH OTHER SALMONELLA SPECIES. INABILITY TO DISTINGUISH CURRENT VS. PREVIOUS INFECTION VS. VACCINATION AGAINST TYPHOID.

12 Dec

ANTI-STREPTOLYSIN O TITRE TEST (ASOT)

December 12, 2022June 5, 2023vincentochiengde

Category

SEROLOGY/ IMMUNOLOGY.

Sub Category

INFECTIOUS

Synonyms/Aliases

STREPTOCOCCAL ANTIBODIES, ANTI-HYALURONIDASE.

Abbreviations

ASOT; ASO.

^Type

INDIVIDUAL TEST.

^{2 HRS}

RESULTS READY IN 2 HRS.

^Method

QUANTITATIVE NEPHELOMETRY.

^Temp

AMBIENT (6 HOURS), REFRIGERATED (7 DAYS), FROZEN (14 DAYS)

^Setup

ALL WORKING DAYS.

Components Parameters

N/A

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

N/A

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

2 ML.

Rejection criteria

Other Instructions

Reference intervals

NEGATIVE; TITRES ARE PROVIDED FOR POSITIVE CASES.

Clinical Utility

EVALUATE RECENT INFECTION WITH AND SEQUELAE OF GROUP A STREPTOCOCCI (GAS) I.E. RHEUMATIC FEVER & POST STREPTOCOCCAL GLOMERULONEPHRITIS.

Test Limitations/ Confounders

ANTIBODIES ARE DETECTED ≥3 WEEKS POST INFECTION.