Special chemistry – ScanLab Center

11 Jun

IgE, TOTAL.

June 11, 2023June 11, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ALLERGY.

Synonyms/Aliases

IMMUNOGLOBULIN E, TOTAL; SERUM IgE.

Abbreviations

IgE

^Type

INDIVIDUAL TEST

^Results

RESULTS READY/ REPORTED IN 5 WORKING DAYS.

^Method

IMMUNOASSAY.

^Temp

REFRIGERATED (2℃-8℃) OR FROZEN.

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

NOT APPLICABLE

Sample type

SERUM

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 3ML

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

SCREENING FOR ALLERGY/ ATOPY. HOWEVER NORMAL LEVELS DO NOT ENTIRELY EXCLUDE IgE.

Test Limitations/ Confounders

LEVELS CAN BE ELEVATED DUE TO OTHER CONDITIONS E.G. PARASITIC INFECTIONS, SOME MALIGNANCIES ETC. LEVELS MAY BE REDUCED IN IMMUNODEFICIENCY.

11 Jun

HIGHLY SENSITIVE C REACTIVE PROTEIN

June 11, 2023June 11, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

INFLAMMATION

Synonyms/Aliases

HIGHLY SENSITIVE CRP, CARDIAC CRP.

Abbreviations

HS CRP

^Type

INDIVIDUAL TEST

^Results

RESULTS READY/ REPORTED IN 2 WORKING DAYS.

^Method

IMMUNOASSAY.

^Temp

REFRIGERATED

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

NOT APPLICABLE

Sample type

SERUM

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

2ML OF SERUM EACH (0MIN, 30, 60, 90, 120MIN) AND COLLECTION SEQUENCE CORRECTLY LABELED ON THE 5 TUBES.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

INTERPRETIVE DATA IS PROVIDED ON THE REPORT.

Clinical Utility

MEASURE OF LOW LEVEL INFLAMMATION, FOR ASSESSING RISK OF DEVELOPING CVD, ACS.

Test Limitations/ Confounders

STATINS, WOMEN ON HORMONE REPLACEMENT THERAPY, PEOPLE WITH CHRONIC INFLAMMATION

11 Jun

GROWTH HORMONE SUPPRESSION BY GLUCOSE

June 11, 2023June 11, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE

Synonyms/Aliases

GH SUPPRESSION TEST

Abbreviations

- N/A

^Type

PROFILE/ PANEL (BUNDLED TESTS)

^Results

RESULTS READY/ REPORTED IN 5 WORKING DAYS

^Method

IMMUNOASSAY.

^Temp

FROZEN (-20°C) PREFERRED OR REFRIGERATED. THERE IS LIMITED STABILITY AT ROOM (AMBIENT) TEMPERATURE AND THIS SHOULD BE AVOIDED.

^Setup

BATCHED.

Components Parameters

0 MIN (BASAL) THEN 30MIN, 60MIN, 90MIN, AND 120MIN GROWTH HORMONE AFTER 75G ORAL GLUCOSE LOAD

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. 75GMS (OR 1.75G/KG OF BODY WEIGHT FOR CHILDREN) OF ORAL GLUCOSE. BASAL GROWTH HORMONE LEVEL 30MIN, 60MIN, 90MIN, AND 120MIN GROWTH HORMONE AFTER ORAL GLUCOSE. CONSENT FORM NEEDED. ORAL GLUCOSE PROCURED SEPARATELY.

Patient preparation

10-12 HOUR FASTING (FASTING MEANS THAT ONLY WATER AND PRESCRIBED MEDICATION IF ANY ARE PERMITTED DURING THE FASTING PERIOD); 30 MINUTES REST PRIOR TO COLLECTION. MULTI-SAMPLING WILL BE PERFORMED.

Sample type

5 SERUM SAMPLES WITH ACCURATE COLLECTION SEQUENCE ON THE SAMPLE LABELS.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

2ML OF SERUM EACH (0MIN, 30, 60, 90, 120MIN) AND COLLECTION SEQUENCE CORRECTLY LABELED ON THE 5 TUBES.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED/ COLLECTION SEQUENCE NOT STATED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE. NONFASTING BASELINE STATUS.

Other Instructions

Reference intervals

INTERPRETIVE DATA IS PROVIDED ON THE REPORT. FAILURE TO ADEQUATELY SUPPRESS IS CONSISTENT WITH AUTOMONOUS GH PRODUCTION E.G. BY ANTERIOR PITUITARY ADENOMAS OR ECTOPIC PRODUCTION.

Clinical Utility

EVALUATION OF SUSPECTED GROWTH HORMONE EXCESS E.G. GIGANTISM, ACROMEGALY.

Test Limitations/ Confounders

INCORRECT LABELING OF COLLECTION SEQUENCE WILL RESULT IN INACCURATE INTERPRETATION. UNFROZEN SAMPLES

11 Jun

HOMOCYSTEINE, SERUM

June 11, 2023June 11, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ANEMIA & NUTRITION

Synonyms/Aliases

HOMOCYSTINE, SERUM

Abbreviations

- N/A

^Type

INDIVIDUAL TEST

^Results

RESULTS READY/ REPORTED IN 7 WORKING DAYS

^Method

IMMUNOASSAY.

^Temp

REFRIGERATED

^Setup

BATCHED.

Components Parameters

0 MIN (BASAL) THEN 30MIN, 60MIN, 90MIN, AND 120MIN GROWTH HORMONE AFTER 75G ORAL GLUCOSE LOAD

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

FASTING SPECIMEN IS PREFERRED.

Sample type

SERUM

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

DIAGNOSE HYPERHOMOCYSTEINEMIA DUE TO ACQUIRED CAUSES (VITAMIN B6, B9, B12 OR FOLIC ACID DEFICIENCY, HYPOTHYROIDISM, RENAL INSUFFICIENCY, SOME DRUGS) OR INHERITED CAUSES (HOMOCYSTINURIA, MTHRF C677T MUTATION ETC.). VITAMIN B12 AND FOLATE CAN BE CONSIDERED AS FOLLOW UP TESTS TO ELEVATED HOMOCYSTEINE RESULTS IF NOT ALREADY PERFORMED. HYPERHOMOCYSTEINEMIA CAN INCREASE THROMBOTIC RISK.

Test Limitations/ Confounders

IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS.

11 Jun

GROWTH HORMONE

June 11, 2023June 11, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE

Synonyms/Aliases

SOMATOTROPIN; SOMATOTROPHIC HORMONE

Abbreviations

GH; HGH

^Type

INDIVIDUAL TEST

^Results

RESULTS READY/ REPORTED IN 7 WORKING DAYS

^Method

IMMUNOASSAY.

^Temp

FROZEN (-20°C) PREFERRED OR REFRIGERATED. THERE IS LIMITED STABILITY AT ROOM (AMBIENT) TEMPERATURE AND THIS SHOULD BE AVOIDED.

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. TO SCREEN FOR GIGANTISM & ACROMEGALY, CONSIDER IGF-1 OR GROWTH HORMONE SUPPRESSION TEST AS ALTERNATE TESTS (BETTER SCREENING TESTS). TO EVALUATE FOR DWARFISM/ SHORT STATURE, CONSIDER GROWTH HORMONE STIMULATION TEST (SPECIFY STIMULANT) AS ALTERNATIVE.

Patient preparation

10-12 HOUR FASTING (FASTING MEANS THAT ONLY WATER AND PRESCRIBED MEDICATION IF ANY ARE PERMITTED DURING THE FASTING PERIOD); 30 MINUTES REST PRIOR TO COLLECTION.

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

DIAGNOSIS OF GROWTH DISORDERS E.G. SHORT STATURE/ DWARFISM, GIGANTISM, ACROMEGALY FROM PITUITARY & HYPOTHALAMIC DISORDERS. EVALUATION OF GROWTH HORMONE EXCESS AND GROWTH HORMONE DEFICIENCY. EVALUATION OF PITUITARY TUMORS. FURTHER TESTS (AS APPLICABLE): STIMULATION TESTS (FOR SUSPECTED GH DEFICIENCY), SUPPRESSION TESTS (FOR SUSPECTED GH EXCESS), IGF-1.

Test Limitations/ Confounders

INTERFERENCE CAN ARISE FROM EATING (FASTING REQUIRED), DRUGS, STRESS, EXERCISE (COLLECT SAMPLES AFTER REST). IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS. HORMONE IS RELEASED IN A PULSATILE MANNER & RAPIDLY CLEARED THEREFORE NORMAL VALUES MAY NOT RULE OUT DISEASE.

11 Jun

GASTRIN

June 11, 2023June 11, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE

Synonyms/Aliases

-N/A

Abbreviations

-N/A

^Type

INDIVIDUAL TEST

^Results

RESULTS READY/ REPORTED IN 7 WORKING DAYS

^Method

IMMUNOASSAY.

^Temp

FROZEN (-20°C). SAMPLES ARE ROOM TEMPERATURE ARE NOT ACCEPTABLE

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

12 -14 HOURS FASTING REQUIRED. FASTING MEANS THAT ONLY WATER & PRESCRIBED MEDICATION IF ANY ARE TAKEN. SHOULD BE OFF DRUGS THAT INHIBIT ACID PRODUCTION (ANTACIDS, PROTON PUMP INHIBITORS, ETC.) FOR AT LEAST 24 HOURS PRIOR IF APPLICABLE.

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.NONFASTING SAMPLES.

Other Instructions

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

DIAGNOSE GASTRIN PRODUCING TUMORS (GASTRINOMAS, ZOLLINGER ELLISON SYNDROME).

Test Limitations/ Confounders

PROTON PUMP INHIBITORS, H2 BLOCKERS INCREASE GASTRIN LEVELS. INCREASED LEVELS OCCUR IN PERNICIOUS ANEMIA, CHRONIC ATROPHIC GASTRITIS.

11 Jun

FREE T4

June 11, 2023June 11, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE

Synonyms/Aliases

THYROXINE

Abbreviations

FT4

^Type

INDIVIDUAL TEST

^Results

RESULTS READY/ REPORTED IN 2-3 HOURS

^Method

IMMUNOASSAY.

^Temp

REFRIGERATED

^Setup

DAILY

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

NOT APPLICABLE

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

DIAGNOSE HYPERTHYROIDISM, HYPOTHYROIDISM & MONITOR TREATMENT FOR THYROID DISEASE.

Test Limitations/ Confounders

11 Jun

FREE T3

June 11, 2023June 11, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE

Synonyms/Aliases

TRIIODOTHYRONINE

Abbreviations

FT3

^Type

INDIVIDUAL TEST

^Results

RESULTS READY/ REPORTED IN 2-3 HOURS

^Method

IMMUNOASSAY.

^Temp

REFRIGERATED

^Setup

DAILY

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

NOT APPLICABLE

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

DIAGNOSE HYPERTHYROIDISM, HYPOTHYROIDISM & MONITOR TREATMENT FOR THYROID DISEASE.

Test Limitations/ Confounders

11 Jun

FREE PROSTATE SPECIFIC ANTIGEN

June 11, 2023June 11, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

TUMOR MARKER

Synonyms/Aliases

FREE PSA

Abbreviations

N/A

^Type

INDIVIDUAL TEST

^Results

RESULTS READY/ REPORTED IN 5 WORKING DAYS.

^Method

IMMUNOASSAY.

^Temp

AMBIENT, REFRIGERATED (PREFERRED) OR FROZEN.

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

NO PREPARATION REQUIRED

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

INTERPRETIVE DATA IS PROVIDED ON THE REPORT.

Clinical Utility

ASSESSING THE RISK OF PROSTATE CANCER IN PATIENTS WITH BORDERLINE OR MODERATELY INCREASED TOTAL PSA.

Test Limitations/ Confounders

11 Jun

FOLLICLE STIMULATING HORMONE

June 11, 2023June 11, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE

Synonyms/Aliases

N/A

Abbreviations

FSH

^Type

INDIVIDUAL TEST

^Results

RESULTS READY/ REPORTED IN 3 HOURS.

^Method

IMMUNOASSAY.

^Temp

AMBIENT, REFRIGERATED (PREFERRED) OR FROZEN.

^Setup

DAILY

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

NO PREPARATION REQUIRED

Sample type

SERUM. HEPARIN PLASMA IS AN ACCEPTABLE ALTERNATE SPECIMEN.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

AGE, GENDER, MENSTRUAL PHASE (FOLLICULAR PHASE VS. MID CYCLE PEAK VS. LUTEAL PHASE), POST MENOPAUSAL REFERENCE INTERVALS (AS APPROPRIATE) ARE PROVIDED ON THE REPORT.

Clinical Utility

ASSESSMENT OF MALE & FEMALE (IN)FERTILITY, AMENORRHEA, OLIGOMENORRHEA, MENSTRUAL IRREGULARITY, MENOPAUSE, HYPOTHALAMIC & PITUITARY DISORDERS, PRECOCIOUS OR DELAYED PUBERTY.

Test Limitations/ Confounders

IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULT INTERPRETATION IS INFLUENCED BY TANNER STAGING (CHILDREN), MENSTRUAL CYCLE PHASE (IN WOMEN OF REPRODUCTIVE AGE), MENOPAUSE.

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