Special chemistry – Page 7

07 Jun

LEVETIRACETAM

June 7, 2023June 7, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

DRUGS/ TDM/ TOXICOLOGY.

Synonyms/Aliases

KEPPRA.

Abbreviations

N/A.

^Type

INDIVIDUAL TEST.

^{7 Days}

RESULTS READY/ REPORTED IN 7 WORKING DAYS.

^Method

QUANTITATIVE IMMUNOASSAY.

^Temp

AT LEAST 2 ML SERUM WITHOUT GEL TUBE.

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE.

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. DETAILED SPECIFIC HISTORY IS REQUIRED E.G. EXACT INDICATION FOR DRUG MONITORING, DRUG HISTORY (I.E. DOSE, ROUTE OF ADMINISTRATION, DURATION SINCE TREATMENT WAS STARTED OR DOSE ADJUSTED, CONCURRENT MEDICATION), HEIGHT, WEIGHT.

Patient preparation

SPECIFIC TIMING APPLIES I.E. COLLECT TROUGH (PRE-DOSE) SAMPLE.

Sample type

SERUM.

Container/ preservative

PLAIN (RED TOP) VACUTAINER. SERUM SEPARATOR TUBES (SST/ GEL) ARE UNACCEPTABLE.

Sample volume

AT LEAST 2 ML SERUM WITHOUT GEL TUBE.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE (INCLUDING SST/ GEL TUBES); INSUFFICIENT SAMPLE; MISSING HISTORY AS EXPOUNDED UNDER TEST ORDERING INSTRUCTIONS.

Other Instructions

CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.

Reference intervals

INTERPRETIVE DATA IS PROVIDED ON THE REPORT.

Clinical Utility

OPTIMIZE DRUG DOSAGE (TO AVOID SUBTHERAPEUTIC & TOXIC DOSES I.E. ENSURE TARGET THERAPEUTIC RANGE IS ACHIEVED); TO VERIFY COMPLIANCE.

Test Limitations/ Confounders

LEVELS ARE INFLUENCED BY DOSAGE REGIMEN, DRUG INTERACTIONS, INDIVIDUAL'S METABOLIZING CAPACITY. SST/ GEL TUBES CAN ADSORB THE DRUG LEADING TO FALSELY LOWERED DRUG LEVELS & SHOULD BE AVOIDED.

07 Jun

LEPTIN, SERUM

June 7, 2023June 7, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE.

Synonyms/Aliases

HUMAN LEPTIN.

Abbreviations

N/A.

^Type

INDIVIDUAL TEST.

^{14 Days}

RESULTS READY/ REPORTED IN 14 WORKING DAYS.

^Method

IMMUNOASSAY.

^Temp

AMBIENT (25℃):6H, R (2℃-8℃):7D, F (-20℃): 30D.

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE.

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

FASTING MEANS THAT ONLY WATER AND PRESCRIBED MEDICATION ARE PERMITTED DURING THE FASTING PERIOD.

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 3 ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

INTERPRETIVE DATA IS PROVIDED ON THE REPORT.

Clinical Utility

HORMONE ESSENTIAL FOR NORMAL BODY WEIGHT REGULATION. OBESITY CAN ARISE FROM LEPTIN DEFICIENCY OR RESISTANCE.

Test Limitations/ Confounders

N/A.

07 Jun

IRON STUDIES PROFILE, SERUM

June 7, 2023June 7, 2023vincentochiengde

Category

PROFILES

Sub Category

ANEMIA & NUTRITION.

Synonyms/Aliases

N/A.

Abbreviations

N/A.

^Type

PROFILE/ PANEL (BUNDLED TESTS).

^{3 Days}

RESULTS READY/ REPORTED IN 3 WORKING DAYS.

^Method

BIOCHEMICAL.

^Temp

AMBIENT (25℃):2H R (2℃-8℃):7D F (-20℃) :30D.

^Setup

BATCHED.

Components Parameters

IRON, TOTAL IRON BINDING CAPACITY (TIBC), TRANSFERRIN SATURATION, FERRITIN.

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

NOT APPLICABLE.

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 3 ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

INTERPRETIVE DATA IS PROVIDED ON THE REPORT.

Clinical Utility

EVALUATION OF IRON DEFICIENCY ANEMIA & IRON OVERLOAD.

Test Limitations/ Confounders

IRON LEVELS ARE AFFECTED BY DIET, ORAL IRON SUPPLEMENTS, RECENT I.V. IRON ADMINISTRATION & DIURNAL VARIATION. FERRITIN IS A POSITIVE ACUTE PHASE REACTANT THEREFORE CONCURRENT INFLAMMATION IS A CONFOUNDING FACTOR.

07 Jun

INTERLEUKIN 6

June 7, 2023June 7, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

INFLAMMATION.

Synonyms/Aliases

CYTOKINE, IL 6 HS.

Abbreviations

IL-6.

^Type

INDIVIDUAL TEST

^{5 Days}

RESULTS READY/ REPORTED IN 5 WORKING DAYS.

^Method

IMMUNOASSAY.

^Temp

FROZEN (PREFERRED). ROOM TEMPERATURE NOT ACCEPTABLE.

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE.

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

NOT APPLICABLE.

Sample type

SERUM, EDTA PLASMA OR HEPARIN PLASMA (SEPARATION VIAL LABEL MUST INCLUDE SAMPLE TYPE.

Container/ preservative

EDTA (PURPLE TOP) VACUTAINER. SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 3 ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE; SAMPLES AT ROOM TEMPERATURE.

Other Instructions

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

CYTOKINE THAT IS USED TO IDENTIFY SEVERE INFLAMMATORY RESPONSE. LIMITED DIAGNOSTIC APPLICATION.

Test Limitations/ Confounders

IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS.

07 Jun

INSULIN-LIKE GROWTH FACTOR 1

June 7, 2023June 7, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE.

Synonyms/Aliases

SOMATOMEDIN-C, SULFATION FACTOR.

Abbreviations

IGF-1; IGF1; SM-C.

^Type

INDIVIDUAL TEST

^{5 Days}

RESULTS READY/ REPORTED IN 5 WORKING DAYS.

^Method

IMMUNOASSAY.

^Temp

FROZEN (-20°C) PREFERRED OR REFRIGERATED. THERE IS LIMITED STABILITY AT ROOM (AMBIENT) TEMPERATURE AND THIS SHOULD BE AVOIDED.

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE.

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

10-12HOURS FASTING REQUIRED. FASTING MEANS THAT ONLY WATER AND PRESCRIBED MEDICATION ARE PERMITTED DURING THE FASTING PERIOD.

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

2 ML SERUM.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE; NON-FASTING SAMPLE.

Other Instructions

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

DIAGNOSIS OF GROWTH DISORDERS E.G. SHORT STATURE/ DWARFISM, GIGANTISM, ACROMEGALY FROM PITUITARY & HYPOTHALAMIC DISORDERS. EVALUATION OF GROWTH HORMONE EXCESS AND GROWTH HORMONE DEFICIENCY.

Test Limitations/ Confounders

LEVELS INFLUENCED BY CHRONIC INFLAMMATORY STATES, NUTRITIONAL DISORDERS, PREGNANCY ETC. IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS.

07 Jun

INHIBIN B

June 7, 2023June 7, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE.

Synonyms/Aliases

N/A.

Abbreviations

N/A

^Type

INDIVIDUAL TEST

^{7 Days}

RESULTS READY/ REPORTED IN 7 WORKING DAYS.

^Method

IMMUNOASSAY.

^Temp

AMBIENT (25℃):1DAY REFRIGERATED (2℃-8℃):2DAYS FROZEN (-20℃): 30 DAYS.

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE.

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. CLINICAL HISTORY IS MANDATORY.

Patient preparation

N/A

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.GROSSLY HEMOLYZED SAMPLES.

Other Instructions

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

DIAGNOSE AND MONITOR FEMALE GONADAL FUNCTION. AN ENDOCRINE MARKER TO ASSESS OVARIAN RESERVE.

Test Limitations/ Confounders

07 Jun

IMMUNOGLOBULIN M

June 7, 2023June 7, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

IMMUNE.

Synonyms/Aliases

IgM TOTAL; SERUM IgM.

Abbreviations

IgM.

^Type

INDIVIDUAL TEST

^{5 Days}

RESULTS READY/ REPORTED IN 5 WORKING DAYS.

^Method

IMMUNOASSAY.

^Temp

REFRIGERATED (2℃-8℃).

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE.

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

N/A

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

EVALUATION OF HYPOGAMMAGLOBULINEMIA, SUSPECTED IgM DEFICIENCY, IgM GAMMOPATHY.

Test Limitations/ Confounders

CHRONIC INFLAMMATORY STATES CAN CAUSE HYPERGAMMAGLOBULINEMIA.

07 Jun

IMMUNOGLOBULIN G

June 7, 2023June 7, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

IMMUNE.

Synonyms/Aliases

IgG TOTAL; SERUM IgG.

Abbreviations

IgG.

^Type

INDIVIDUAL TEST

^{5 Days}

RESULTS READY/ REPORTED IN 5 WORKING DAYS.

^Method

IMMUNOASSAY.

^Temp

REFRIGERATED (2℃-8℃).

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE.

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

N/A

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

EVALUATION OF HYPOGAMMAGLOBULINEMIA, SUSPECTED IgG DEFICIENCY, IgG GAMMOPATHY.

Test Limitations/ Confounders

CHRONIC INFLAMMATORY STATES CAN CAUSE HYPERGAMMAGLOBULINEMIA.

07 Jun

IMMUNOGLOBULIN A

June 7, 2023June 7, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

IMMUNE.

Synonyms/Aliases

IgA TOTAL; SERUM IgG.

Abbreviations

IgA.

^Type

INDIVIDUAL TEST

^{5 Days}

RESULTS READY/ REPORTED IN 5 WORKING DAYS.

^Method

IMMUNOASSAY.

^Temp

REFRIGERATED (2℃-8℃).

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE.

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

N/A

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

EVALUATION OF HYPOGAMMAGLOBULINEMIA, SUSPECTED IgA DEFICIENCY, IgA GAMMOPATHY.

Test Limitations/ Confounders

CHRONIC INFLAMMATORY STATES CAN CAUSE HYPERGAMMAGLOBULINEMIA.

07 Jun

IgG, SUBCLASS 4

June 7, 2023June 7, 2023vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

IMMUNE.

Synonyms/Aliases

IMMUNOGLOBULIN G, SUBCLASS 4.

Abbreviations

IgG4.

^Type

INDIVIDUAL TEST

^{7 Days}

RESULTS READY/ REPORTED IN 7 WORKING DAYS.

^Method

IMMUNOASSAY.

^Temp

REFRIGERATED (2℃-8℃).

^Setup

BATCHED.

Components Parameters

NOT APPLICABLE.

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY.

Patient preparation

N/A

Sample type

SERUM.

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

DIAGNOSIS OF IgG4-RELATED DISEASES E.G. AUTOIMMUNE PANCREATITIS INLAMMATORY ORBITAL PSEUDOTUMOR, SCLEROSING SILADENITIS ETC.

Test Limitations/ Confounders

ELEVATED LEVELS CAN OCCUR IN OTHER DISORDERS E.G. ALLERGY.

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