11 Jun

C-PEPTIDE

vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE

Synonyms/Aliases

CONNECTING PEPTIDE OF INSULIN

Abbreviations

-N/A

Type

INDIVIDUAL TEST

Results

RESULTS READY/ REPORTED 7 WORKING DAYS

Method

IMMUNOASSAY

Temp

FROZEN (PREFERRED) OR REFRIGERATED. LIMITED STABILITY AT AMBIENT (ROOM) TEMPERATURE WHICH SHOULD BE AVOIDED.

Setup

BATCHED.

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. HISTORY REQUIRED.

Patient preparation

OVERNIGHT FASTING (8-12HRS). FASTING MEANS THAT ONLY WATER AND PRESCRIBED MEDICATION ARE PERMITTED DURING THE FASTING PERIOD.

Sample type

SERUM

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE; AMBIENT TEMPERATURE. NON-FASTING SAMPLES.

Other Instructions

CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.

Reference intervals

AGE & GENDER APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

EVALUATION OF PANCREATIC BETA CELL FUNCTION (E.G. TO DISTINGUISH TYPE 1 VS. TYPE 2 DIABETES). WORK UP OF HYPERINSULINEMIC HYPOGLYCEMIA (E.G. DIFFERENTIATE BETWEEN FACTITIOUS HYPOGLYCEMIA & POSSIBLE INSULINOMAS). C-PEPTIDE IS CO-PRODUCED WITH ENDOGENOUS INSULIN & IS THEREFORE A USEFUL MARKER OF INSULIN PRODUCTION.

Test Limitations/ Confounders

IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS.
11 Jun

CORTISOL, 24 HR URINE

vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE

Synonyms/Aliases

-N/A

Abbreviations

-N/A

Type

INDIVIDUAL TEST

Results

RESULTS READY/ REPORTED 5 WORKING DAYS.

Method

IMMUNOASSAY

Temp

REFRIGERATED.

Setup

BATCHED.

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. TOTAL VOLUME OF COLLECTED 24 HOUR URINE IS REQUIRED.

Patient preparation

ACCURATELY TIMED 24 HOUR COLLECTION (E.G. 6A.M., DAY 1 TO 6A.M., DAY 2) IS CRUCIAL FOR RESULT ACCURACY. COLLECT URINE IN A CLEAN WIDE MOUTH CONTAINER & TRANSFER ENTIRE COLLECTION INTO THE CONTAINER THAT WAS PROVIDED BY THE LAB. REFRIGERATE DURING COLLECTION. KEEP OUT OF REACH OF CHILDREN (CONTAINS CORROSIVE SUBSTANCES).

Sample type

24 HOUR URINE

Container/ preservative

USE 10 GM OF BORIC ACID PRESERVATIVE.

Sample volume

10ML ALIQUOT OF 24 HOUR URINE. ORIGINAL (TOTAL) VOLUME IN ML MUST BE SPECIFIED ON THE REQUEST FORM.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.SAMPLE COLLECTED OUTSIDE THE SPECIFIED TIME

Other Instructions

NOT APPLICABLE

Reference intervals

INTERPRETIVE DATA IS PROVIDED ON THE REPORT.

Clinical Utility

EVALUATION OF CUSHING'S SYNDROME, CUSHING'S DISEASE (HYPERCORTISOLISM) AND ADDISON'S DISEASE (HYPOCORTISOLISM).

Test Limitations/ Confounders

USE OF STEROIDS AFFECTS RESULTS. IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS.
11 Jun

CORTISOL (PM)

vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE

Synonyms/Aliases

-N/A

Abbreviations

-N/A

Type

INDIVIDUAL TEST

Results

RESULTS READY/ REPORTED 2-4 HRS

Method

IMMUNOASSAY

Temp

FROZEN PREFERRED OR REFRIGERATED. AMBIENT (ROOM) TEMPERATURE NOT ACCEPTABLE.

Setup

DAILY

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. COLLECT BETWEEN 4-6 PM

Patient preparation

COLLECT BETWEEN 4-6 PM

Sample type

SERUM

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE. SAMPLE COLLECTED OUTSIDE THE SPECIFIED TIME

Other Instructions

CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.

Reference intervals

EVALUATION OF CUSHING'S SYNDROME, CUSHING'S DISEASE (HYPERCORTISOLISM) AND ADDISON'S DISEASE (HYPOCORTISOLISM).

Clinical Utility

EVALUATION OF CUSHING'S SYNDROME, CUSHING'S DISEASE (HYPERCORTISOLISM) AND ADDISON'S DISEASE (HYPOCORTISOLISM).

Test Limitations/ Confounders

USE OF STEROIDS AFFECTS RESULTS. IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS.
11 Jun

CORTISOL (AM)

vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE

Synonyms/Aliases

-N/A

Abbreviations

-N/A

Type

INDIVIDUAL TEST

Results

RESULTS READY/ REPORTED 2-4 HRS.

Method

IMMUNOASSAY

Temp

FROZEN PREFERRED OR REFRIGERATED. AMBIENT (ROOM) TEMPERATURE NOT ACCEPTABLE.

Setup

DAILY

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. COLLECT BETWEEN 8-9 AM

Patient preparation

COLLECT BETWEEN 8-9 AM

Sample type

SERUM (COLLECT BETWEEN 8-9 AM)

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.SAMPLE COLLECTED OUTSIDE THE SPECIFIED TIME

Other Instructions

CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.

Reference intervals

REFERENCE RANGES APPLY FOR SAMPLES COLLECTED BETWEEN 7-10 A.M. CORTISOL UNDERGOES DIURNAL VARIATION WITH PEAK CONCENTRATION OCCURRING AT 6 A.M. TO 8 A.M.

Clinical Utility

EVALUATION OF CUSHING'S SYNDROME, CUSHING'S DISEASE (HYPERCORTISOLISM) AND ADDISON'S DISEASE (HYPOCORTISOLISM).

Test Limitations/ Confounders

USE OF STEROIDS AFFECTS RESULTS. IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS.
11 Jun

COMPLEMENT C4

vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

IMMUNE

Synonyms/Aliases

COMPLEMENT COMPONENT 3

Abbreviations

C4

Type

INDIVIDUAL TEST

Results

RESULTS READY/ REPORTED IN 5 WORKING DAYS.

Method

IMMUNOTURBIDIMETRY

Temp

FROZEN PREFERRED OR REFRIGERATED. AMBIENT (ROOM) TEMPERATURE NOT ACCEPTABLE.

Setup

BATCHED.

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. PROVIDE DETAILED CLINICAL HISTORY.

Patient preparation

FASTING. FOR 10-12HRS

Sample type

SERUM (10-12 HR FASTING SAMPLE PREFERRED).

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.NONFASTING SAMPLE.

Other Instructions

CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.

Reference intervals

APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

SUSPECTED COMPLEMENT CONSUMPTION (E.G. IN SLE, CRYOGLOBULINEMIA). MONITORING DISEASE ACTIVITY, GLOMERULONEPHRITIS IN SLE. EVALUATION OF RECURRENT UNEXPLAINED BACTERIAL INFECTIONS, ATYPICAL HEMOLYTIC UREMIC SYNDROME OR HEREDITARY ANGIOEDEMA.

Test Limitations/ Confounders

TEMPERATURE SENSITIVE ANALYTE. ANALYTE IS A POSITIVE ACUTE PHASE REACTANT. LEVELS AFFECTED BY COMPLEMENT INHIBITORY DRUGS E.G. ECULIZUMAB.
11 Jun

COMPLEMENT C3

vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

IMMUNE

Synonyms/Aliases

COMPLEMENT COMPONENT 3

Abbreviations

C3

Type

INDIVIDUAL TEST

Results

RESULTS READY/ REPORTED IN 5 WORKING DAYS.

Method

IMMUNOTURBIDIMETRY

Temp

FROZEN PREFERRED. AMBIENT (ROOM) TEMPERATURE NOT ACCEPTABLE.

Setup

BATCHED.

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. PROVIDE DETAILED CLINICAL HISTORY.

Patient preparation

10-12 HRS. FASTING PREFERRED.

Sample type

SERUM

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.

Reference intervals

APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

SUSPECTED COMPLEMENT CONSUMPTION (E.G. IN SLE, CRYOGLOBULINEMIA). MONITORING DISEASE ACTIVITY, GLOMERULONEPHRITIS IN SLE. EVALUATION OF RECURRENT UNEXPLAINED BACTERIAL INFECTIONS OR ATYPICAL HEMOLYTIC UREMIC SYNDROME.

Test Limitations/ Confounders

TEMPERATURE SENSITIVE ANALYTE. ANALYTE IS A POSITIVE ACUTE PHASE REACTANT. LEVELS AFFECTED BY COMPLEMENT INHIBITORY DRUGS E.G. ECULIZUMAB.
11 Jun

CHROMOGRANIN A

vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

ENDOCRINE; TUMOR MARKER

Synonyms/Aliases

-N/A

Abbreviations

CgA

Type

INDIVIDUAL TEST

Results

RESULTS READY/ REPORTED IN 7-10 WORKING DAYS.

Method

CHROMATOGRAPHY

Temp

FROZEN (PREFERRED). AVOID REFRIGERATION.

Setup

BATCHED.

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. PROVIDE DETAILED CLINICAL HISTORY.

Patient preparation

NO PREPARATION REQUIRED.

Sample type

EDTA PLASMA

Container/ preservative

EDTA (PURPLE TOP) VACUTAINER

Sample volume

2ML EDTA PLASMA

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

CENTRIFUGE EDTA VACUTAINER AND ALIQUOT PLASMA. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.

Reference intervals

APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

MONITORING OF NEUROENDOCRINE TUMORS E.G. CARCINOID TUMORS, PHEOCHROMOCYTOMA, PARAGANGLIOMA, NEUROBLASTOMAAMINE & PRECURSOR UPTAKE & DECARBOXYLATION (APUD) TUMORS.

Test Limitations/ Confounders

LEVELS MAY ALSO BE ELEVATED IN RENAL FAILURE, INFLAMMATORY CONDITIONS, PPI THERAPY ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS & RESULTS OF OTHER DIAGNOSTIC WORK-UP E.G. IMAGING, TISSUE BIOPSY FINDINGS.
11 Jun

CATECHOLAMINES, PLASMA

vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

TUMOR MARKER

Synonyms/Aliases

FRACTIONATED CATECHOLAMINES, PLASMA.

Abbreviations

N/A

Type

PROFILE/ PANEL (BUNDLED TESTS)

Results

RESULTS READY/ REPORTED IN 10 - 14 DAYS

Method

CHROMATOGRAPHY

Temp

FROZEN ONLY. AMBIENT AND REFRIGERATED TEMPERATURE UNACCEPTABLE.

Setup

BATCHED.

Components Parameters

EPINEPHRINE (ADRENALINE) & NOREPINEPHRINE (NORADRENALINE).

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. PROVIDE CLINICAL HISTORY & PATIENT'S CURRENT DRUG HISTORY. DISCONTINUE ANTIHYPERTENSIVE DRUGS IF FEASIBLE (MULTIPLE DRUGS CAN INCREASE OR DECREASE CATECHOLAMINE LEVELS; CONSULT PATHOLOGIST IF IN DOUBT).

Patient preparation

DISCONTINUE HYPERTENSION RELATED MEDICATION (TO BE DECIDED BY ATTENDING DR/ CLINICIAN). DO NOT CONSUME FOODS RICH IN SEROTONIN (E.G. BANANAS, PINEAPPLE, CEREALS, POTATOES, COFFEE, TEA, CHOCOLATE, VANILLA ETC.) FOR 72 HOURS PRIOR TO SAMPLE COLLECTION. AVOID STRENUOUS EXERCISE.

Sample type

EDTA PLASMA

Container/ preservative

EDTA (PURPLE TOP) VACUTAINER

Sample volume

2ML EDTA PLASMA

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE; UNFROZEN SAMPLES,

Other Instructions

CENTRIFUGE EDTA WHOLE BLOOD IMMEDIATELY, SEPARATE PLASMA AND FREEZE.

Reference intervals

APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

CATECHOLAMINE TESTS ARE MOST OFTEN USED TO DIAGNOSE OR RULE OUT CERTAIN TYPES OF RARE TUMORS, INCLUDING: PHEOCHROMOCYTOMA, NEUROBLASTOMA, PARAGANGLIOMA

Test Limitations/ Confounders

DIETARY & DRUG INTERFERENCE CAN OCCUR. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS & RESULTS OF OTHER DIAGNOSTIC WORK-UP E.G. IMAGING, TISSUE BIOPSY FINDINGS.
11 Jun

CATECHOLAMINES, 24 HOUR URINE

vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

TUMOR MARKER

Synonyms/Aliases

FRACTIONATED CATECHOLAMINES, 24 HR URINE.

Abbreviations

N/A

Type

PROFILE/ PANEL (BUNDLED TESTS)

Results

RESULTS READY/ REPORTED IN 10 - 14 DAYS

Method

CHROMATOGRAPHY

Temp

FROZEN (PREFERRED) OR REFRIGERATED.

Setup

BATCHED.

Components Parameters

EPINEPHRINE (ADRENALINE) & NOREPINEPHRINE (NORADRENALINE).

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. TOTAL VOLUME OF COLLECTED 24 HOUR URINE IS REQUIRED. PROVIDE CLINICAL HISTORY & PATIENT'S CURRENT DRUG HISTORY. DISCONTINUE ANTIHYPERTENSIVE DRUGS IF FEASIBLE (MULTIPLE DRUGS CAN INCREASE OR DECREASE CATECHOLAMINE LEVELS; CONSULT PATHOLOGIST IF IN DOUBT).

Patient preparation

ACCURATELY TIMED 24 HOUR COLLECTION (E.G. 6A.M., DAY 1 TO 6A.M., DAY 2) IS CRUCIAL FOR RESULT ACCURACY. COLLECT URINE IN A CLEAN WIDE MOUTH CONTAINER & TRANSFER ENTIRE COLLECTION INTO THE CONTAINER THAT WAS PROVIDED BY THE LAB. REFRIGERATE DURING COLLECTION. KEEP OUT OF REACH OF CHILDREN (CONTAINS CORROSIVE SUBSTANCES). DO NOT CONSUME FOODS RICH IN SEROTONIN (E.G. BANANAS, PINEAPPLE, CEREALS, POTATOES, COFFEE, TEA, CHOCOLATE, VANILLA ETC.) FOR 72 HOURS PRIOR TO SAMPLE COLLECTION. AVOID STRENUOUS EXERCISE.

Sample type

24 HOUR URINE.

Container/ preservative

CLEAN CONTAINER WITH 10ML OF 6N HCL PRESERVATIVE ISSUED BY THE LAB.

Sample volume

10ML ALIQUOT OF 24 HOUR URINE. ORIGINAL (TOTAL) VOLUME IN ML MUST BE SPECIFIED ON THE REQUEST FORM.

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE; 24 HOUR URINE VOLUME NOT PROVIDED.

Other Instructions

NOT APPLICABLE

Reference intervals

APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

CATECHOLAMINE TESTS ARE MOST OFTEN USED TO DIAGNOSE OR RULE OUT CERTAIN TYPES OF RARE TUMORS, INCLUDING: PHEOCHROMOCYTOMA, NEUROBLASTOMA, PARAGANGLIOMA

Test Limitations/ Confounders

DIETARY & DRUG INTERFERENCE CAN OCCUR. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS & RESULTS OF OTHER DIAGNOSTIC WORK-UP E.G. IMAGING, TISSUE BIOPSY FINDINGS.
11 Jun

CARCINOEMBRYONIC ANTIGEN

vincentochiengde

Category

SPECIAL CHEMISTRY.

Sub Category

TUMOR MARKER

Synonyms/Aliases

EMBRYONIC CARCINOMA ANTIGEN

Abbreviations

CEA

Type

INDIVIDUAL TEST

Results

RESULTS READY/ REPORTED IN 2 -3 HOURS

Method

IMMUNOASSAY

Temp

REFRIGERATED

Setup

DAILY

Components Parameters

NOT APPLICABLE

PRE-ANALYTIC CONSIDERATIONS

Test Ordering Instructions

FILL OUT TEST REQUEST FORM FULLY & LEGIBLY. DETAILED SPECIFIC HISTORY IS REQUIRED E.G. EXACT INDICATION FOR DRUG MONITORING, DRUG HISTORY (I.E. DOSE, ROUTE OF ADMINISTRATION, DURATION SINCE TREATMENT WAS STARTED OR DOSE ADJUSTED, CONCURRENT MEDICATION), HEIGHT, WEIGHT.

Patient preparation

NO PREPARATION REQUIRED

Sample type

SERUM

Container/ preservative

SERUM SEPARATOR TUBE (SST/ GEL) OR PLAIN (RED TOP) VACUTAINER.

Sample volume

AT LEAST 2ML

Rejection criteria

LABELING ISSUE (UNLABELED/ MISLABELED); MISSING REQUEST FORM; MISMATCH BETWEEN REQUEST FORM & SAMPLE DETAILS; MISSING AGE/ GENDER; WRONG SAMPLE TYPE; INSUFFICIENT SAMPLE.

Other Instructions

CENTRIFUGE SST (SERUM GEL TUBES) WITHIN 1-2 HOURS OF COLLECTION. CENTRIFUGE RED TOP VACUTAINERS AND ALIQUOT SERUM WITHIN 1-2 HOURS OF COLLECTION. THE SEPARATION VIAL MUST BE LABELED WITH AT LEAST 2 PATIENT IDENTIFIERS AND THE SAMPLE TYPE.

Reference intervals

APPROPRIATE VALUES ARE PROVIDED ON THE REPORT.

Clinical Utility

MONITORING TREATMENT RESPONSE, DISEASE PROGRESSION & ASSESSING RECURRENCE IN COLORECTAL CANCER. LEVELS MAY ALSO BE ELEVATED IN OTHER CANCERS E.G. GASTRIC, ESOPHAGEAL, GALL BLADDER, PANCREATIC, BREAST, LUNG, MEDULLARY THYROID CARCINOMA ETC.

Test Limitations/ Confounders

LEVELS MAY BE ELEVATED IN MULTIPLE BENIGN CONDITIONS E.G. SMOKING, HEPATITIS, LIVER CIRRHOSIS, EMPHYSEMA, PANCREATITIS, INFLAMMATORY BOWEL DISEASE ETC. IMMUNOASSAY INTERFERENCE CAN GIVE RISE TO SPURIOUS RESULTS. SUCH INTERFERENCE CAN ARISE FROM PRESENCE OF HETEROPHILE ANTIBODIES, ANTI-ANIMAL ANTIBODIES, AUTOANTIBODIES, PARAPROTEINS, BIOTIN ETC. RESULTS SHOULD ALWAYS BE CORRELATED WITH CLINICAL FINDINGS.
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